School of Medicine - Clinical MedicineGeneral Internal Medicine



As part of the Multidisciplinary Center, the Department of General Internal Medicine was established in April, 2012, integrating and expanding three outpatient clinics: Lifestyle Related Diseases, Kampo (Sino-Japanese traditional medicine), and Women’s General Medicine.
In the field of lifestyle-related diseases, we promote research with a focus on metabolic syndrome, obesity, dyslipidemia, diabetes, and hypertension. For patients suspected of visceral fat accumulation (VFA), we use inbody and/or bioelectrical impedance analysis. We also conduct epidemiological studies on dyslipidemia, which is closely related to the pathogenesis of arteriosclerotic diseases such as familial hypercholesterolemia. Furthermore, we investigate the dynamics of lipid metabolizing enzymes as a predictive factor for cardiovascular events.
In the field of Kampo, we study the pathogenesis of chronic fatigue syndrome (CFS) using CF model mice. Specifically, we suspect the involvement of the central nervous system in the etiology of CFS and have examined the functional and morphological changes of the hippocampus. In the future, we aim to elucidate the pathological conditions of CFS through immunostaining and Polymerase Chain Reaction (PCR) for each organ and establish biomarkers for CFS.
In the field of women’s general medicine, we provide comprehensive medical care specifically for women. We also seek to build the foundations for new gender-specific medicine through team medical care as well as by supporting female doctors.

Contact Information

TEL: 076-286-2211(内線5404、5401) +81-76-286-2211  / FAX: 076-286-2702 +81-76-286-2702  / Email:



  • NAKAHASHI Takeshi
  • UENISHI Hiroaki
  • FURUTA Hisakazu

Associate Professor

  • AKAZAWA Sumiyo
  • MORIYA Junji

Assistant Professor

  • SAWADA Mio
  • YAMAZAKI Naruhiro

Research Achievements

Research Activities

  • Kakuda H, Kobayashi J, Kakuda M, Yamakawa J, Takekoshi N.The effect of anagliptin treatment on glucose metabolism and lipid metabolism, and oxidative stress in fasting and postprandial states using a test meal in Japanese men with type 2 diabetes. Endocrine, 2015 ;48:1005-9.
  • Yamakawa J, Moriya J, Takeuchi K, Nakatou M, Motoo Y, Kobayashi J. Significance of Kampo, Japanese traditional medicine, in the treatment of obesity: basic and clinical evidence. Evid Based Complement Alternat Med. 2013;2013:943075.
  • Moriya J, Chen R, Yamakawa J, Sasaki K, Ishigaki Y, Takahashi T. Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells., Biol.Pharm.Bull., 34: 354-359, 2011.
  • Noguchi T, Kobayashi J, Yagi K et al. Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus: Results from a crossover study. Atherosclerosis. 217:165-170, 2011.
  • Yamakawa J, Moriya J, Takahashi T, Ishige A, Motoo Y, Yoshizaki F, Kanda T. A Kampo medicine, boiogito, inhibits obesity in ovariectomized rats, Evid Based Complement Alternat Med, 7:87-95, 2010.

External Research Funding

  • Sciences Research Grant Grant-in-Aid for Scientific Research (C) Grant-in-Aid for Scientific Research ‘The clarification of measuring lipid metabolism enzymes as predictors of cardiovascular events” (2015-2017)
  • Sciences Research Grant Grant-in-Aid for Scientific Research (C) Grant-in-Aid for Scientific Research “The clarification of measuring lipid metabolism enzymes as predictors of the development of non-alcoholic steatohepatitis” (2011-2013)
  • Sciences Research Grant for Young Scientists (B) “Revitalization of the central nervous system in Chinese medicine treatment of Chronic Fatigue Syndrome”(2008-2010)
  • Sciences Research Grant Grant-in-Aid for Scientific Research (C) “The inverse agonist activity of the angiotensin II type 1 receptor antagonist”(2006)
  • Sciences Research Grant Grant-in-Aid for Scientific Research (C) “Analysis of the effect of Boiogito on the metabolic syndrome “ (2006)